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Confirmation of the structure of nisin and its major degradation product by FAB-MS and FAB-MS/MS

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Summary

FAB-MS has been applied to the analysis of a nisin complex and FAB-MS and FAB-MS/MS data from the major component used to provide confirmation of the amino sequence and positions of the sulphur-bridged rings in these highly modified peptides.

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Authors and Affiliations

  1. Department of Chemistry, University of Manchester Institute of Science and Technology, M60 1QD, Manchester, UK

    M. Barber & G. J. Elliot

  2. VG Analytical Ltd, M23 9LE, Wythenshawe, UK

    R. S. Bordoli & B. N. Green

  3. Department of Pharmacy, University of Nottingham, NG7 2RD, Nottingham, UK

    B. W. Bycroft

Authors
  1. M. Barber
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  2. G. J. Elliot
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  3. R. S. Bordoli
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  4. B. N. Green
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  5. B. W. Bycroft
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Barber, M., Elliot, G.J., Bordoli, R.S. et al. Confirmation of the structure of nisin and its major degradation product by FAB-MS and FAB-MS/MS. Experientia 44, 266–270 (1988). https://doi.org/10.1007/BF01941734

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  • DOI: https://doi.org/10.1007/BF01941734

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