, Volume 44, Issue 3, pp 228–230 | Cite as

Enhancement of the cytogenetic efficacy of the antitumor agent bleomycin by the calcium and calmodulin antagonist fendiline

  • W. Scheid
  • H. Traut
Short Communications


The induction of chromosome aberrations (dicentric and ring chromosomes) in human lymphocytes by the antitumor agent bleomycin is synergistically enhanced when bleomycin is applied together with the calcium antagonist fendiline (Sensit®).

Key words

Bleomycin calcium antagonist calmodulin antagonist chromosome aberrations comutagenesis cytostatics fendiline lymphocytes verapamil 


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Copyright information

© Birkhäuser Verlag 1988

Authors and Affiliations

  • W. Scheid
    • 1
  • H. Traut
    • 1
  1. 1.Institut für StrahlenbiologieUniversität MünsterMünster(Federal Republic of Germany)

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