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Experientia

, Volume 42, Issue 7, pp 823–825 | Cite as

The potent tremorgenic neurotoxins lolitrem B and aflatrem: A comparison of the tremor response in mice

  • R. T. Gallagher
  • A. D. Hawkes
Short Communications

Summary

Tremor dose-response curves were determined for mice dosed with the ryegrass neurotoxin lolitrem B, and the tremorgenic mycotoxin aflatrem. A family of characteristic curves was revealed for each tremorgen, with lolitrem B eliciting a sustained tremor response persisting for over 24 h.

Key words

Tremorgenic neurotoxins indoles lolitrem B aflatrem mice tremor dose-response, ryegrass staggers 

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Copyright information

© Birkhäuser Verlag Basel 1986

Authors and Affiliations

  • R. T. Gallagher
    • 1
  • A. D. Hawkes
    • 1
  1. 1.Ruakura Animal Research StationMinistry of Agriculture and FisheriesHamilton(New Zealand)

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