, Volume 42, Issue 9, pp 1038–1040 | Cite as

Possible involvement of protein kinase C in the stimulation of amino acid transport by phorbol ester, platelet-derived growth factor and A23187 in Swiss 3T3 cells

  • K. Kitagawa
  • H. Nishino
  • A. Iwashima
Short Communications


Stimulation of amino acid transport induced by phorbol-12, 13-dibutyrate, platelet-derived growth factor or A23187 was not observed in cells lacking protein kinase C. On the other hand, stimulation of transport by epidermal growth factor or insulin was not affected. These results suggested that the stimulation of amino acid transport is mediated by at least two separate pathways.

Key words

Amino acid transport protein kinase C calcium ion mouse fibroblast 


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Copyright information

© Birkhäuser Verlag Basel 1986

Authors and Affiliations

  • K. Kitagawa
    • 1
  • H. Nishino
    • 1
  • A. Iwashima
    • 1
  1. 1.Department of BiochemistryKyoto Prefectural University of MedicineKyoto(Japan)

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