Experientia

, Volume 46, Issue 10, pp 1057–1060 | Cite as

Effects of serotonin and ketanserin on the functional morphology of chick down feather bulbi in vitro

  • H. Beele
  • H. Thierens
  • B. Verhasselt
  • L. de Ridder
Research Articles

Summary

Chick feather bulbi cultured in vitro showed an increased DNA synthesis and a delayed keratinization after treatment with ketanserin, a serotonin2 antagonist with wound-healing properties. In contrast, serotonin stimulates keratinization of the keratinocytes in the bulbus.

Key words

Organotypic cultures feather bulbus keratinocytes serotonin ketanserin 

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Literature

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Copyright information

© Birkhäuser Verlag Basel 1990

Authors and Affiliations

  • H. Beele
    • 1
  • H. Thierens
    • 2
  • B. Verhasselt
    • 1
  • L. de Ridder
    • 1
  1. 1.Laboratory for HistologyState University of GentGent(Belgium)
  2. 2.Laboratory for Medical PhysicsState University of GentGent(Belgium)

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