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Experientia

, Volume 44, Issue 5, pp 444–446 | Cite as

Distal axonopathy in streptozotocin diabetes in rats

  • S. Chokroverty
  • D. Seiden
  • P. Navidad
  • R. Cody
Short Communications

Summary

We noted the earliest morphological changes in the motor endplates 8 weeks after the induction of streptozotocin diabetes in rats. Morphometric measurements showed reduced axonal areas of the lateral plantar and the sicatic nerves in the diabetic rats 28 but not 2 and 8 weeks after the experiment. These findings suggested distal axonopathy.

Key words

Streptozotocin rats diabetic distal axonopathy 

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Copyright information

© Birkhäuser Verlag 1988

Authors and Affiliations

  • S. Chokroverty
    • 1
    • 2
  • D. Seiden
    • 1
    • 2
  • P. Navidad
    • 1
    • 2
  • R. Cody
    • 1
    • 2
  1. 1.The Neurology ServiceVA Medical CenterLyonsUSA
  2. 2.Departments of NeurologyAnatomy and Environmental and Community Medicine, UMDNJ-Robert Wood Johnson Medical SchoolNew Brunswick and PiscatawayUSA

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