, Volume 43, Issue 4, pp 445–446 | Cite as

Photoreactivation of UV damage in culturedDrosophila cells

  • T. M. Koval
Short Communications


Cell survival and photoreactivation of 254 nm ultraviolet (UV) light damage in a wild typeDrosophila cell line was assayed by colony formation in liquid medium. Fo, Fq, and extrapolation number for the exponential portion of survival curves are 21 J/m2, 3.6 J/m2, and 1.5 for non-photoreactivated cells and 110 J/m2, 11.2 J/m2, and 1.3 for those exposed to photoreactivating light. Maximal photoreactivation occurs at the 100 J/m2 region of the curve. At 10 and 50% survival, 75–80% of the UV damage was photoreactivable.

Key words

Cell survival photoreactivation insect cell Drosophila colony formation DNA repair ultraviolet radiation 


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Copyright information

© Birkhäuser Verlag 1987

Authors and Affiliations

  • T. M. Koval
    • 1
  1. 1.George Washington University School of Medicine and Health SciencesWashingtonUSA

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