Experientia

, Volume 43, Issue 4, pp 426–428 | Cite as

Cross-reactive monoclonal antibodies to alcohol dehydrogenases

  • B. G. Talbot
  • G. Bilodeau
Short Communications

Summary

Three anti-horse liver alcohol dehydrogenase (HLADH) monoclonal antibodies are described. Two are specific for ADH and cross-react with class I and II enzymes from mouse, horse and Chinese hamster. They are specific for the native enzyme but do not inhibit enzyme activity except when combined at high concentration. The third antibody was isolated as a response to rabbit metallothionein. It binds metalloproteins and inhibits ADH activity.

Key words

Monoclonal antibodies alcohol dehydrogenase 

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Copyright information

© Birkhäuser Verlag 1987

Authors and Affiliations

  • B. G. Talbot
    • 1
  • G. Bilodeau
    • 1
  1. 1.Département de biologie, Faculté des sciencesUniversité de SherbrookeSherbrookeCanada

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