, Volume 46, Issue 7, pp 767–770 | Cite as

Oxytoxins, bioactive molecules produced by the marine opisthobranch molluscOxynoe olivacea from a diet-derived precursor

  • G. Cimino
  • A. Crispino
  • V. Di Marzo
  • M. Gavagnin
  • J. D. Ros
Research Articles


The ethereal extract of the mucous secretion from the opisthobranch molluscOxynoe olivacea was examined and found to contain two novel ichthyotoxic compounds, named oxytoxin 1 and 2 (1, 2). The structures of1 and2 are closely related to the metabolites previously isolated from the algaCaulerpa prolifera. The activity of the most stable compound was studied in order to investigate the possibility, of a further biological role for these metabolites, which represent an uncommon example of bioactive molecules produced in vivo from a dietary precursor.

Key words

Opisthobranch molluscs defense mechanisms marine toxins dialdehydes 


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Copyright information

© Birkhäuser Verlag Basel 1990

Authors and Affiliations

  • G. Cimino
    • 1
  • A. Crispino
    • 1
  • V. Di Marzo
    • 1
  • M. Gavagnin
    • 1
  • J. D. Ros
    • 2
  1. 1.Istituto per la Chimica di Molecole d'Interesse Biologico del C. N. R.Napoli(Italy)
  2. 2.Department d'Ecologia, Facultat de BiologiaUniversitat de BarcelonaBarcelona(Spain)

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