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Experientia

, Volume 31, Issue 7, pp 829–831 | Cite as

Cytotoxicity and carcinogenicity of pterosins and pterosides, 1-indanone derivatives from bracken (Pteridium aquilinum)

  • M. Saito
  • M. Umeda
  • M. Enomoto
  • Y. Hatanaka
  • S. Natori
  • K. Yoshihira
  • M. Fukuoka
  • M. Kuroyanagi
Specialia Pharmacologica

Keywords

Carcinogenicity Pteridium Aquilinum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Über 30 Chemikalien aus getrockneten jungen Blättern und Wurzelstöcken des japanischen FarnkrautesPteridium aquilinum wurden isoliert und als Sesquiterpen-Derivate mit 1-Indanonkern, Pterosine und deren Glukoside, Pteroside, identifiziert. Eine nur geringe Toxizität für HeLa-Zellen ohne Chromosomenschädigung wurde festgestellt. Langzeitfütterung von Pterosin B und Pterosid B ergab keine Tumorbildung in Wistar-Ratten, obwohl die rohen Blätter und Wurzelstöcke kanzerogen waren.

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Copyright information

© Birkhäuser Verlag 1975

Authors and Affiliations

  • M. Saito
    • 1
    • 2
  • M. Umeda
    • 1
    • 2
  • M. Enomoto
    • 1
    • 2
  • Y. Hatanaka
    • 1
    • 2
  • S. Natori
    • 1
    • 2
  • K. Yoshihira
    • 1
    • 2
  • M. Fukuoka
    • 1
    • 2
  • M. Kuroyanagi
    • 1
    • 2
  1. 1.Institute of Medical ScienceUniversity of TokyoTokyo(Japan)
  2. 2.National Institute of Hygienic SciencesTokyo(Japan)

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