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Conversion ofβ-sitosterol to steroid hormones by rat testes in vitro

  • Specialia Chimica, Biochimica
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Résumé

Les mitochondries des cellules testiculaires de rat convertissent le β-sitostérol-4-C14 en prégnénolone et progestérone. Comme celle du cholestérol, l'oxydation du β-sitostérol en composés stéroidiens est stimulée par le NADPH. La radio-chromatographie en phase gazeuse des stéroides n'indique aucune conversion du β-sitostérol en cholestérol on en stéroides à 27 carbones dans les conditions étudiées.

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Author notes

  1. M. T. R. Subbiah

    Present address: Cardio Vascular Research Unit, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

Authors and Affiliations

  1. Department of Biochemistry and Banting and Best Department of Medical Research, University of Toronto, 112, College Street, M5G 1L6, Toronto, Ontario, Canada

    M. T. R. Subbiah & A. Kuksis

Authors
  1. M. T. R. Subbiah
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  2. A. Kuksis
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Additional information

These studies were supported by grants from the Ontario Heart Foundation, Toronto, Ontario and the Medical Research Council of Canada.

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Subbiah, M.T.R., Kuksis, A. Conversion ofβ-sitosterol to steroid hormones by rat testes in vitro. Experientia 31, 763–764 (1975). https://doi.org/10.1007/BF01938448

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  • DOI: https://doi.org/10.1007/BF01938448

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