Experientia

, Volume 30, Issue 8, pp 928–930 | Cite as

Interaction between 6-hydroxydopamine and rhodopsin in vivo in the rat retina

  • S. F. Pong
  • L. T. GrahamJr.
Pharmacologica

Keywords

Retina Nous Avons 

Résumé

Nous avons observé que l'injection de la 6-hydroxydopamine dans l'humeur vitrée des rats adaptés à la lumière bloquait le rétablissement de la sensibilité rétinale pendant l'adaptation à l'obscurité subséquente au traitement. Il est possible que cette observation soit une conséquence de la réaction du produit de l'oxydation de la 6-hydroxydopamine avec les groupes nucléophiliques de la rhodopsine.

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Copyright information

© Birkhäuser Verlag 1974

Authors and Affiliations

  • S. F. Pong
    • 1
  • L. T. GrahamJr.
    • 1
  1. 1.Section of Neurobiology, The Institute of Psychiatric ResearchIndiana University Medical CenterIndianapolisUSA

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