Experientia

, Volume 32, Issue 2, pp 183–184 | Cite as

Cross-resistance of trichomonads to 5-nitroimidazole-derivatives

  • J. G. Meingassner
  • H. Mieth
Article

Summary

The strainT. foetus KV 1/M 100, a sub-strain ofT. foetus Kv 1, was made highly resistant to metronidazole by several passages in mice under increasing drug pressure. This drug resistance was accompained by a remarkable cross-resistance to all 5-nitroimidazole-derivatives tested in vitro and in vivo.

Keywords

Drug Resistance Metronidazole Drug Pressure 

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • J. G. Meingassner
    • 1
  • H. Mieth
    • 1
  1. 1.Sandoz Forschungsinstitut Gesellschaft m.b.H.Wien(Austria)

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