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Roquefortine and isofumigaclavine A, metabolites fromPenicillium roqueforti

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The structures of two metabolites fromPenicillium roqueforti, designated roquefortine and isofumigaclavine A, have been determined by chemical and spectroscopic studies.

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  1. Acknowledgements. We thankS. Moreau for mycelium ofP. roqueforti andJ.-C. Gripon and MlleE. Zissmann for additional cultures;B. Septe for13C nmr-spectra:S. K. Kan for the 240 MHz1H nmr-spectrum of roquefortine; MmeLe Phan Diêp for amino acid analyses; andS. Wilkinson andP. G. Mantle, respectively, for samples of fumigaclavine B and agroclavine.

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Scott, P.M., Merrien, MA. & Polonsky, J. Roquefortine and isofumigaclavine A, metabolites fromPenicillium roqueforti. Experientia 32, 140–142 (1976).

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