Antibiotic activity of organic compounds and their average quasi-valence number
It is shown that the average quasi-valence numbers of antibiotics inhibiting protein synthesis are well defined and lie in the region of average quasi-valence numbers of amino acids, while the average quasi-valence numbers of antibiotics inhibiting DNA or RNA synthesis have higher values. Possible explanations of these findings and their implications on the design and selection of antibiotics are discussed.
KeywordsOrganic Compound Protein Synthesis Inhibit Protein Synthesis Antibiotic Activity Antibiotic Inhibit Protein Synthesis
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