, Volume 34, Issue 5, pp 619–621 | Cite as

Electrogenic hyperpolarization in canine cardiac Purkinje fibres exposed to calcium ionophores

  • J. M. Gelles
  • R. Zeiler


The Ca ionophores markedly enhance the increase of intracellular Ca occurring during Na-free perfusion and the hyperpolarization observed upon Na readmission may be due to rapid restoration of intracellular Na and resultant stimulation of both electrogenic sodium and calcium efflux.


Sodium Calcium Calcium Ionophore Purkinje Fibre Rapid Restoration 
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Copyright information

© Birkhäuser Verlag 1978

Authors and Affiliations

  • J. M. Gelles
    • 1
  • R. Zeiler
    • 1
  1. 1.Department of MedicineDownstate Medical Center of the State University of New YorkBrooklynUSA

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