, Volume 33, Issue 1, pp 91–93 | Cite as

Adhesion and aggregation of human platelets to rabbit subendothelium. A new approach for investigation: Specific antibodies

  • J. P. Caen
  • H. Michel
  • G. Tobelem
  • E. Bodevin
  • S. Levy-Toledano


An IgG antibody occurring in a recently transfused thrombasthenic patient inhibited all the ADP-mediated aggregations and platelet-platelet interaction (thrombus formation) on rabbit aorta subendothelium; another IgG antibody occurring in a multitransfused Bernard-Soulier patient inhibited ristocetin and bovine factor VIII mediated aggregation and platelet-subendothelium interaction.


Specific Antibody Factor VIII Thrombus Formation Human Platelet Rabbit Aorta 
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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • J. P. Caen
    • 1
  • H. Michel
    • 1
  • G. Tobelem
    • 1
  • E. Bodevin
    • 1
  • S. Levy-Toledano
    • 1
  1. 1.INSERM, U. R. 150, C. N. R. S., E. R. A. 335Hôpital LariboisièreParis-Cedex 10(France)

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