, Volume 33, Issue 1, pp 12–13 | Cite as

Diketopiperazines containing L-proline from Streptomyces lavendulae and their stereochemistry in solution

  • A. Kubo
  • K. Takahashi
  • T. Arai


l-Valyl-l-proline (I),l-leucyl-l-proline (II),l-phenylalanyl-l-proline (III) andl-isoleucyl-l-proline (IV) anhydrides were isolated from the cultures ofStreptomyces lavendulae No. 314 and, on the basis of13C-NMR and CD spectra, their stereochemistry in solution is described.


Anhydride Streptomyces Diketopiperazines 
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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • A. Kubo
    • 1
    • 2
    • 3
  • K. Takahashi
    • 1
    • 2
    • 3
  • T. Arai
    • 1
    • 2
    • 3
  1. 1.Laboratory of Organic ChemistryMeiji College of PharmacySetagaya TokyoJapan
  2. 2.Division of ChemotherapyChiba Cancer Center Research InstituteNitona ChibaJapan
  3. 3.Department of Antibiotics Research Institute for ChemobiodynamicsChiba UniversityIzumi NarashinoJapan

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