Skip to main content
Log in

Basal blood pressure variability and reactivity of blood pressure to emotional stress in essential hypertension

  • Original Contributions
  • Published:
Basic Research in Cardiology Aims and scope Submit manuscript

Summary

Blood pressure variability under basal conditions and blood pressure reactivity to emotional stress were studied in 38 hypertensives and 13 normotensives.

Systolic basal blood pressure variability correlated with systolic blood pressure reactivity. Variability increased with higher basal blood pressure. Thus in the hypertension group the blood pressure variability was greater than in the normotension group. Besides, the hypertension group showed a greater reactivity of systolic blood pressure to emotional stress, too. An influence of age on basal blood pressure, blood pressure variability, and reactivity could be evaluated; but no influence of sex on these parameters was detected.

The results indicate that variability and reactivity of blood pressure can be referred to a common central nervous blood-pressure-regulating mechanism. As both parameters are increased in hypertension, a greater lability of blood pressure must be assumed. This greater lability may be attributed to a stronger neurogenic influence or to structural changes of peripheral blood vessels.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bevan AT, Honour AJ, Stott FH (1969) Direct arterial pressure recording in unrestricted man. Clin Sci 36:329–344

    PubMed  Google Scholar 

  2. Birkenhäger WH, van Es LA, Houwing A, Lamers HJ, Mulder AH (1968) Studies on the lability of hypertension in man. Clin Sci 35:445–456

    PubMed  Google Scholar 

  3. Clement DL, Mussche MM, Vanhoutte G, Pannier R (1979) Is blood pressure variability related to activity of the sympathetic system? Clin Sci 57:217s-219s

    PubMed  Google Scholar 

  4. v Eiff AW, Plotz EJ, Beck KJ, Czernik A (1971) The effect of estrogens and progestins on blood pressure regulation of normotensive women. Amer J Obstet Gynecol 109:887–892

    Google Scholar 

  5. v Eiff AW, Schulte W, Heusch G (1979) Classification of homogeneous blood pressure groups and the specific hemodynamic pattern of borderline hypertension. In: Yamori Y, Lovenberg W, Freis ED (eds) Prophylactic approach to hypertensive diseases. Perspectives in cardiovascular research. Raven Press, New York

    Google Scholar 

  6. v Eiff AW, Friedrich GM, Gogolin E, Lutz HM, Neus H, Schulte W (1982) Weibliche Sexualhormone als Risiko- und Schutzfaktoren für den Blutdruck. Verh Dtsch Ges inn Med 88:779–783

    Google Scholar 

  7. Goldberg AD, Raftery EB, Cashman PMM, Stott FD (1978) Study of untreated hypertensive subjects by means of continuous intra-arterial blood pressure recordings. Br Heart J 40:656–664

    PubMed  Google Scholar 

  8. Kain HK, Hinman AT, Sokolow M (1964) Arterial blood pressure measurements with a portable recorder in hypertensive patients. I. Variability and correlation with “casual” pressures. Circulation 30:882–892

    PubMed  Google Scholar 

  9. Krönig B (1976) Blutdruckvariabilität bei Hochdruckkranken. Ergebnisse telemetrischer Langzeitmessungen. Hüthig, Heidelberg

    Google Scholar 

  10. Krönig B, Knappen F (1977) Spezielle Aspekte der Blutdruckvariabilität Hochdruckkranker. Herz/Kreislauf 9:499–502

    Google Scholar 

  11. de Leeuw PW, Kho TL, Falke HE, Birkenhäger WH, Wester A (1978) Haemodynamic and endocrinological profile of essential hypertension. Acta Med Scand Suppl 622

  12. de Leeuw PW, Birkenhäger WH (1980) Arterieller Blutdruck-der variable Parameter. In: Rosenthal J (Hrsg) Arterielle Hypertonie; Ätiopathogenese, Diagnostik und Therapie, Springer, Berlin Heidelberg New York

    Google Scholar 

  13. Littler WA, Honour AJ, Pugsley DJ, Sleight P (1975) Continuous recording of direct arterial pressure in unrestricted, patients. Its role in the diagnosis and management of high blood pressure. Circulation 51:1101–1106

    PubMed  Google Scholar 

  14. Littler WA, Honour AJ, Carter RD, Sleight P (1975) Sleep and blood pressure. Br Med J III, 346–348

    Google Scholar 

  15. Littler WA, West MJ, Honour AJ, Sleight P (1978) The variability of arterial pressure. Am Heart J 95:180–186

    PubMed  Google Scholar 

  16. Lorimer AR, Macfarlane PW, Provan G, Duffy T, Lawrie TDV (1971) Blood pressure and catecholamine responses to “stress” in normotensive and hypertensive subjects. Cardiovasc Res 5:169–173

    PubMed  Google Scholar 

  17. Mancia G, Ferrari A, Gregorini L, Parati G, Pomidossi G, Bertinieri G, Grassi G, Zanchetti A (1980) Blood pressure variability in man: its relation to high blood pressure, age and baroreflex sensitivity. Clin Sci 59:401s-404s

    PubMed  Google Scholar 

  18. Melville DI, Raftery EB (1981) Blood pressure changes during acute mental stress in hypertensive subjects using the Oxford intra-arterial system. J Psychosom Res 25:487–497

    PubMed  Google Scholar 

  19. Millar-Craig MW, Bishop CN, Raftery EB (1978), Circadian variation of blood-pressure. Lancet I, 795–797

    Google Scholar 

  20. Nestel PJ (1969) Blood-pressure and catecholamine excretion after mental stress in labile hypertension. Lancet I, 692–694

    Google Scholar 

  21. Noffke HU, Schirmer G (1981) Indirekte Blutdruckmessung mit einem Zwei-Sonden-Ultraschallsystem. Biomed Techn 26:162–167

    Google Scholar 

  22. Ogawa J, Arai S, Takata S, Ikeda T, Takabatake T, Hattori N, Nomura G (1981) Daily profile of baroreflex sensitivity and the variability of blood pressure in essential hypertensive patients. Cli Sci 61:157s-159s

    Google Scholar 

  23. Pessina AC, Mormino P, Semplicini A, Palatini P, Casiglia E, Hlede M, Dal Palu C (1980) The blood pressure in “labile” and “established” hypertension: Computer analysis of the continuous blood pressure recording. In: Stott FD, Raftery EB, Goulding L (eds) Proceedings of the Third International Symposium on Ambulatory Monitoring (ISAM 1979). Academic Press, London New York

    Google Scholar 

  24. Pickering TG, Harshfield GA, Kleinert HD, Blank S, Laragh JH (1982) Blood pressure during normal daily activities, sleep, and excrcise. JAMA 247:992–996

    PubMed  Google Scholar 

  25. Richardson DW, Honour AJ, Fenton GW, Stott FH, Pickering GW (1964) Variation in arterial pressure throughout the day and night. Clin Sci 26:445–460

    PubMed  Google Scholar 

  26. Sayers BMcA (1980) Data processing workshop. Introduction: Analysis of intra-arterial blood pressure records. In: Stott FD, Raftery EB, Goulding L (eds) Proceedings of the Third International Symposium on Ambulatory Monitoring (ISAM 1979). Academic Press, London, New York

    Google Scholar 

  27. Sayers BMcA, Cicchiello LR, Raftery EB, Mann S, Green H (1982) The assessment of continuous ambulatory blood pressure records. Med Inform 7:93–108

    Google Scholar 

  28. Schmieder R, Neus H, Schulte W (1982) Zur Beziehung zwischen Blutdruckvariabilität und Blutdruckreaktivität bei essentieller Hypertonie. Med Welt 33:939–940

    PubMed  Google Scholar 

  29. Schroeder HA, Menhard EM (1956) Spontaneous variations of blood pressure in hypertensive and normotensive individuals. Am Heart J 51:577–587

    PubMed  Google Scholar 

  30. Schulte W, Neus H (1979) Bedeutung von Streßeraktionen in der Hypertoniediagnostik. Herz/Kreislauf 11:541–546

    Google Scholar 

  31. Schulte W, Neus H v Eiff AW (1981) Blutdruckreaktivität unter emotionalem Streß bei unkomplizierten Formen des Hochdrucks. Klin Wochenschr 59:1243–1249

    PubMed  Google Scholar 

  32. Schulte W, Fehring C, Neus H (1983) Cardiovascular reactivity to ergometric exercise in mild hypertension. Cardiology 70:50–56

    Google Scholar 

  33. Shapiro AP, Moutsos SE, Krifcher E (1963) Patterns of pressor response to noxious stimuli in normal, hypertensive, and diabetic subjects. J clin Invest 42:1890–1898

    PubMed  Google Scholar 

  34. Sokolow M, Werdegar D, Kain HK, Hinman AT (1966) Relationship between level of blood pressure measured casually and by portable recorders and severity of complications in essential hypertension. Circulation 34:279–298

    PubMed  Google Scholar 

  35. Voudoukis IJ (1978) Cold pressor test and hypertension. Angiology 29:429–439

    PubMed  Google Scholar 

  36. Watson RDS, Stallard TJ, Flinn RM, Littler WA (1980) Factors determining direct arterial pressure and its variability in hypertensive man. Hypertension 2:333–341

    PubMed  Google Scholar 

  37. WHO (1962) Arterial hypertension and ischaemic heart disease Preventive aspects. WHO techn report ser No 231

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schulte, W., Neus, H., Thönes, M. et al. Basal blood pressure variability and reactivity of blood pressure to emotional stress in essential hypertension. Basic Res Cardiol 79, 9–16 (1984). https://doi.org/10.1007/BF01935802

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01935802

Key words

Navigation