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Evidence for a modulation of the stress response by the pineal gland

Experientia volume 46, pages 860–862 (1990)Cite this article

Summary

Wistar rats show a circadian variation in their response to stress. Pinealectomy exacerbates stress-induced gastric ulceration in rats. This effect is counteracted by melatonin administration.

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References

  1. The authors would like to thank Mrs S. Morley for her technical assistance.

  2. This work was supported by grants from the Medical Research Council of South Africa and the Rhodes University Council to Professor B. Potgieter.

  3. Axelrod, J., Science184 (1974) 1341.

    PubMed  Google Scholar 

  4. Minneman, K. P., and Wurtman, R. J., Life Sci.17 (1984) 1189.

    Article  Google Scholar 

  5. Vaughan, G. M., Allen, J. P., Tullis, W., Sackman, J. W., and Vaughan, M. K., Neurosci. Lett.91 (1978) 83.

    Article  Google Scholar 

  6. Lynch, H. J., Eng, J. P., and Wurtman, R. J., Proc. natl Acad. Sci.70 (1973) 227.

    Google Scholar 

  7. Tannenbaum, M. G., Reiter, R. J., Vaughan, M. K., Troiani, M. E., and Gonzalez-Brito, A., Cryobiology25 (1988) 227.

    Article  PubMed  Google Scholar 

  8. Miline, R., J. neural Trans.47 (1980) 191.

    Article  Google Scholar 

  9. Romijn, H. J., Life Sci.23 (1978) 2257.

    Article  PubMed  Google Scholar 

  10. Mehdi, A. Z., and Sandor, T., J. Steroid Biochem.8 (1977) 821.

    Article  PubMed  Google Scholar 

  11. Dickson, K. L., and Hasty, D. L., Acta endocr.70 (1972) 438.

    PubMed  Google Scholar 

  12. Pare, W. P., and Glavin, G. B., Neurosci. Biobehav. Rev.10 (1986) 339.

    Article  PubMed  Google Scholar 

  13. Maestroni, G. J. M., Conti, A., and Pierpaoli, W., Immunology63 (1988) 465.

    PubMed  Google Scholar 

  14. Senay, E. C., and Levine, R. J., Proc. Soc. exp. Med.124 (1967) 1221.

    Google Scholar 

  15. Khan, R., Burton, S., Morley, S., Daya, S., and Potgieter, B., Experientia46 (1990) 88.

    PubMed  Google Scholar 

  16. Hoffman, R. A., and Reiter, R. J., Anat Rec.153 (1965) 19.

    Article  PubMed  Google Scholar 

  17. Reiter, R. J., (ed.), The Pineal Gland, vol. 111, Extra Reproductive Effects, pp. 90–96. CRC Press, Florida 1982.

    Google Scholar 

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Author information

Affiliations

  1. School of Pharmaceutical Sciences, Rhodes University, P.O. Box 94, 6140, Grahamstown, South Africa

    R. Khan & B. Potgieter

  2. Department of Biochemistry, Rhodes University, P.O. Box 94, 6140, Grahamstown, South Africa

    S. Daya

Authors
  1. R. Khan
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  2. S. Daya
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  3. B. Potgieter
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Khan, R., Daya, S. & Potgieter, B. Evidence for a modulation of the stress response by the pineal gland. Experientia 46, 860–862 (1990). https://doi.org/10.1007/BF01935539

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  • DOI: https://doi.org/10.1007/BF01935539

Key words

  • Pineal gland
  • stress
  • melatonin