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Structural basis for resetting of baroreceptor regulation in spontaneously hypertensive rats (SHR)

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Zusammenfassung

Nachweis, dass in Ratten mit genetischem Hochdruck und normalem Herzrhythmus Verdickungen des Endotheliums im Karotissinus und im Aortabogen beobachtet werden. Eine Hypertrophie der Gefässmuskulatur war nachweisbar, was zu einer Abschwächung des Drucksignals zur Stelle der Pressorezeptoren führte. Diese dürften teilweise verantwortlich sein für die Verschiebung der Pressorezeptor-Steuerung bei genetisch hypertensiven Ratten.

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Author information

Authors and Affiliations

  1. Depts. for Cardiovascular Research and Cell Biology, Janssen Pharmaceutica, Koninklijke laan 17, B-2340, Beerse, Belgium

    D. Wellens, M. Borgers & A. Verheyen

Authors
  1. D. Wellens
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  2. M. Borgers
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  3. A. Verheyen
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Additional information

This study is partly supported by I.W.O.N.L.

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Wellens, D., Borgers, M. & Verheyen, A. Structural basis for resetting of baroreceptor regulation in spontaneously hypertensive rats (SHR). Experientia 29, 1268–1271 (1973). https://doi.org/10.1007/BF01935111

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