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Acquisition of an embryonal biochemical feature in the rat liver after portacaval shunt

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Zusammenfassung

In Leberhomogenaten von Ratten mit einem portocavalen «Shunt» wurde gegenüber unbehandelten Kontrolltieren eine zehnfache Vermehrung der Aktivität der γ-Glutamyltranspeptidase festgestellt. Dieser Befund könnte als Derepression dieses Enzyms gedeutet werden, da ähnlich gesteigerte Enzymaktivitäten bisher nur bei embryonalen Lebern und bei chemisch induzierten Hepatomen gemessen worden sind.

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Authors and Affiliations

  1. Chemisches Zentrallabor, Inselspital Berne, CH-3010, Bern, Switzerland

    J. P. Colombo & J. Bircher

  2. Department of Clinical Pharmacology, University of Berne, CH-3010, Bern, Switzerland

    J. P. Colombo & J. Bircher

Authors
  1. J. P. Colombo
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  2. J. Bircher
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Colombo, J.P., Bircher, J. Acquisition of an embryonal biochemical feature in the rat liver after portacaval shunt. Experientia 29, 1232–1233 (1973). https://doi.org/10.1007/BF01935089

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