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Effect of age on distribution of acidic glycosaminoglycans in normal human urine: Special reference to proportion of chondroitin sulfate A to the C-isomer

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Résumé

Le sulfate A de chondroitine est un acide glycosaminoglycanes principal chez les enfants normaux. Mais cette substance diminue avec l'age, tandis que le sulfate C de chondroïtine a une tendance à augmenter. Il en résulte une diminution, de l'action du sulfate A sur le sulfate C. La prépondérence du sulfate C de chondroïtine se manifeste après l'adolescence. Il augmente continuellement au cours de la vie.

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Literatur

  1. N. di Ferrante, J. lab. clin. Med.61, 633 (1963).

    PubMed  Google Scholar 

  2. D. P. Varadi, J. A. Cifonelli andA. Dorfman, Biochim. biophys. Acta141, 103 (1967).

    Article  CAS  PubMed  Google Scholar 

  3. E. Wessler, Biochem. J.122, 373 (1971).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. D. Allalouf andA. Ber, Biochim. biophys. Acta201, 61 (1970).

    Article  CAS  PubMed  Google Scholar 

  5. N. Taniguchi, Clin. chim. Acta37, 225 (1972).

    Article  CAS  PubMed  Google Scholar 

  6. K. Murata, T. Ishikawa andY. Oshima, Clin. chim. Acta28, 213 (1970).

    Article  CAS  PubMed  Google Scholar 

  7. K. Murata, T. Harada, T. Fujiwara andT. Furuhashi, Biochem. biophys. Acta230, 583 (1971).

    Article  CAS  PubMed  Google Scholar 

  8. Chondroitinase-ABC degrades chondroitin sulfates A and B to the unsaturated 4-sulfated disaccharides and chondroitin sulfate C to the unsaturated 6-sulfated disaccharides; the detailed information appeared in ref. 6, 7, 9.

  9. T. Yamagata, H. Saito, O. Habuchi andS. Suzuki, J. biol. Chem.243, 1523 (1968).

    Article  CAS  PubMed  Google Scholar 

  10. Generous gifts from Dr.M. B. Mathews, University of Chicago.

  11. H. Saito, T. Yamagata andS. Suzuki, J. biol. Chem.243, 1536 (1968).

    Article  CAS  PubMed  Google Scholar 

  12. T. Bitter andH. M. Muir, Analyt. Biochem.4, 330 (1962).

    Article  CAS  PubMed  Google Scholar 

  13. D. Kaplan andK. Meyer, Nature, Lond.183, 1267 (1959).

    Article  CAS  PubMed  Google Scholar 

  14. M. B. Mathews andS. Glagov, J. clin. Invest.45, 1103 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Acknowledgments. Grateful thanks are due to Prof.Y. Horiuchi for his interest and encouragement. We are indebted to Dr.T. Ishikawa and Dr.H. Ninomiya for preparing normal human urine. The present study was supported by a grant in aid for scientific research from the Education Ministry in Japan.

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Murata, K. Effect of age on distribution of acidic glycosaminoglycans in normal human urine: Special reference to proportion of chondroitin sulfate A to the C-isomer. Experientia 29, 1219–1221 (1973). https://doi.org/10.1007/BF01935081

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