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Effects of glycine and serine on serine hydroxymethyltransferase levels in logarithmic cultures ofNeurospora crassa wild type andSer-1 mutant

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Résumé

Dans un milieu minimal la glycine et la sérine, ajoutées en concentrations physiologiques, augmentent le taux de la sérine-hydroxyméthyltransférase durant la croissance logarithmique duNeurospora crassa. La glycine influence également la synthèse de cet enzyme chez le mutantSer-1 deNeurospora. Ainsi la glycine exogène exerce une régulation de la sérine-hydroxyméthyltransférase et cet enzyme joue un rôle possible dans la synthèse de la sérine dans cet organisme en phase logarithmique de croissance.

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Acknowledgements. This investigation was supported by grant No. 3.540.71 from the Fond National Suisse de la Recherche Scientifique. E.A.C. was the recipient of a National Research Council of Canada travel fellowship. The authors thank MlleMartine Gourjon for excellent technical assistance.

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Cossins, E.A., Combepine, G. & Turian, G. Effects of glycine and serine on serine hydroxymethyltransferase levels in logarithmic cultures ofNeurospora crassa wild type andSer-1 mutant. Experientia 29, 1203–1206 (1973). https://doi.org/10.1007/BF01935071

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