Summary
The authors study the number of mastocytes and the percentage of degranulated types in rats treated with potassium perchlorate. This product has an antithyroid activity. An increase in absolute number of mastocytes in the thyroid gland of treated animals is shown. There is also an increase of degranulated types of these cells. In the other organs (skin, liver, lungs) a decrease in absolute number of mastocytes is observed with a concomitant increase of degranulated types. The results are discussed according to the literature.
Similar content being viewed by others
Rerefences
H. Selye, The Mast Cells (Butterworths, Washington 1965).
J. W. Combs, J.Cell Biol.31, 563 (1966).
W. Raab, Z. Immunitätsforsch.133, 180 (1967).
A. Spreca, M. Laszlo etJ. P. Musy, Acta pharm. Helv.48, 297 (1973).
T. Yamada, Endocrinology81, 1285 (1967).
S. S. Spicer, Am. J. Path.37, 457 (1960).
A. Spreca, L. Modis etG. Conti, J. Embryol. exp. Morph.26, 459 (1971).
L. Lampé, L. Modis etA. Gehl, Acta med. hung.23, 223 (1967).
F. Santini, Arch. ital. Anat. Embriol.67, 443 (1962).
A. Melander, Ch. Owmann etF. Sundler, Endocrinology89, 528 (1971).
G. Ziliotto etN. Pellegrini, Riv. Anat. Pat.11, 903 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Spreca, A., Musy, J.P. Comportement des mastocytes chez les rats traités au perchlorate de potassium. Experientia 30, 278–279 (1974). https://doi.org/10.1007/BF01934827
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01934827