Experientia

, Volume 33, Issue 12, pp 1627–1629 | Cite as

Chlorinated benzene induction of hepatic porphyria

  • G. P. Carlson
Specialia Pharmacologica

Summary

1,4-Dichlorobenzene and 1,2,4-trichlorobenzene were compared with hexachlorobenzene which is known to cause porphyria. Although hexachlorobenzene administration resulted in a manyfold increase in liver porphyrin levels and urinary excretion of porphyrins, the lesser chlorinated compounds did not do so.

Keywords

Benzene Chlorinate Porphyrin Urinary Excretion Porphyria 

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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • G. P. Carlson
    • 1
  1. 1.Department of Pharmacology and Toxicology, School of Pharmacy and Pharmacal SciencesPurdue UniversityWest LafayetteUSA

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