Experientia

, Volume 32, Issue 8, pp 994–995 | Cite as

Nucleolar hypertrophy and nuclear DNA replication in liver

  • R. P. Bailey
  • J. Short
  • I. Lieberman
Specialia Biologica
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Summary

Hypertrophy of nucleoli is associated with DNA synthesis in the hepatocytes of untreated rats just as it is in stimulated animals. Nucleolar enlargement is not a sufficient change to ensure that the parenchymal liver cell can make DNA.

Keywords

Liver Cell Parenchymal Liver Parenchymal Liver Cell Sufficient Change Nucleolar Enlargement 

Literature

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    H. Swift, L. Rebhun, E. Rasch andJ. Woodard, inCellular Mechanisms in Differentiation and Growth (Ed.D. Rudnick; Princeton University Press, Princeton, New Jersey 1956), p. 45.Google Scholar
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    S. Chaudhuri, O. Doi andI. Lieberman, Biochim. biophys. Acta134, 479 (1967).Google Scholar
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    R. P. Bailey, W. A. Rudert, J. Short andI. Lieberman, J. biol. Chem.250, 4305 (1975).PubMedGoogle Scholar
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    M. J. Karnovsky, J. Cell Biol.27, 137A (1965).Google Scholar
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    J. Short, K. Tsukada, W. A. Rudert andI. Lieberman, J. biol. Chem.250, 3602 (1975).PubMedGoogle Scholar

Copyright information

© Birkhäuser-Verlag 1976

Authors and Affiliations

  • R. P. Bailey
    • 1
    • 2
  • J. Short
    • 1
    • 2
  • I. Lieberman
    • 1
    • 2
  1. 1.Department of Anatomy and Cell BiologyUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Veterans Administration HospitalPittsburghUSA

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