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Experientia

, Volume 32, Issue 1, pp 83–84 | Cite as

Effect of colchicine on polymerization of tubulin from rats, mice, hamsters and guinea-pigs

  • T. J. Fitzgerald
  • D. G. Mayfield
Specialia

Summary

Colchicine-inhibition of polymerization of tubulin from rats, mice, golden hamsters and guinea-pigs was studied to determine if species differences in tubulin sensitivity to colchicine might parallel species variation in colchicine toxicity. It was found that polymerization of tubulin is nearly equally sensitive to colchicine in all four species.

Keywords

Polymerization Toxicity Species Variation Colchicine Species Difference 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • T. J. Fitzgerald
    • 1
  • D. G. Mayfield
    • 1
  1. 1.School of PharmacyFlorida A & M UniversityTallahasseeUSA

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