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The effect of short-term treatment of low dose of Methallibure (ICI compound 33,828) on the testis and thumb pad of skipper frog,Rana cyanophlyctis (Schn.)

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Zussammenfassung

Die Behandlung des männlichen FroschesRana cyanophlyctis mit Methallibur (ICI Verbindung 33, 828) während der Dauer von vier Wochen ergab die folgenden Wirkungen: 1. Rückbildung der Leydigschen Zellen und Abnahme ihrerΔ 5-3β-HSDH-Aktivität, 2. Anstieg des Totalgehaltes an Cholesterol, und 3. Rückbildung der Daumenschwielen. Bedeutende histologische und histochemische Veränderungen der Samenkanälchen wurden jedoch nicht beobachtet.

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Supported by a grant No. 4756 from the U.G.C. of India.

Supported by a grant No. M66.117 from the Population Council, Bio Medical Division, New York.

We are grateful to Imperial Chemical Industries Limited, England, for the free gift of Methallibure and to Dr.M. A. Rao for providing laboratory facilities.

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Saidapur, S.K., Ganihar, S.R. & Nadkarni, V.B. The effect of short-term treatment of low dose of Methallibure (ICI compound 33,828) on the testis and thumb pad of skipper frog,Rana cyanophlyctis (Schn.). Experientia 31, 612–613 (1975). https://doi.org/10.1007/BF01932488

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