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The effect of drugs on the release of endogenous catecholamines into the perfusate of discrete brain areas of the cat in vivo

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Zusammenfassung

Hirnregionen der gallamin-immobilisierten Katze wurde mittels «push-pull»-Kanülen perfundiert. Die im Perfusat freigesetzten endogenen Katecholamine wurden radioenzymatisch gemessen. Chlorpromazin,d-Amphetamin oder Oxotremorin (i. v.) erhöhten den «output» von Dopamin aus dem Nucleus caudatus und Chlorpromazin zusätzlich denjenigen von hypothalamischem Noradrenalin durch verschiedene Mechanismen.

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Author notes

  1. K. G. Lloyd

    Present address: Department of Psychopharmacology, Clarke Institute of Psychiatry, 250 College St., Toronto, Canada

Authors and Affiliations

  1. Department of Experimental Medicine, F. Hoffmann-La Roche & Co. Ltd., CH-4002, Basel, Switzerland

    K. G. Lloyd & G. Bartholini

Authors
  1. K. G. Lloyd
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  2. G. Bartholini
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Lloyd, K.G., Bartholini, G. The effect of drugs on the release of endogenous catecholamines into the perfusate of discrete brain areas of the cat in vivo. Experientia 31, 560–562 (1975). https://doi.org/10.1007/BF01932458

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