Advertisement

Experientia

, Volume 34, Issue 11, pp 1478–1479 | Cite as

Determination of infarct size in rats with86rubidium

  • H. Braselmann
  • Ulrike Osswald
  • K. Wenzelides
  • E. Seidler
Article

Summary

A quick method is presented which allows the determination of infarct sizes within hearts of experimental animals like rats. The method is based on the drop of86Rb uptake in infarcted hearts, and has been compared with infarct sizes determined morphometrically. The standard deviation of this method is low (6.5%) because an internal standard is used (noninfarcted myocard-usually right ventricle tissue-has been used).

Keywords

Standard Deviation Experimental Animal Infarct Size Infarcted Heart Quick Method 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literatur

  1. 1.
    P.R. Maroko, P. Libby, C.M. Bloor, B.E. Sobel and E. Braunwald, Circulation46, 430 (1972).PubMedGoogle Scholar
  2. 2.
    K. Wenzelides and R. Meyer, Dte. Gesundhwes.30, 229 (1975).Google Scholar
  3. 3.
    H. Braselmann, K. Sajkiewiicz, U. Osswald, B. Bausdorf and Ch. Ramm, Exp. Path.12, 285 (1976).Google Scholar
  4. 4.
    R.H. Adrian, J. Physiol., Lond.175, 134 (1964).Google Scholar
  5. 5.
    W.D. Love and G.E. Burch, J. clin. Invest.36, 479 (1957).PubMedGoogle Scholar
  6. 6.
    M.M. Nachlass, K.C. Tsou, E. DeSouza, C.S. Cheng and A.M. Seligman, J. Histochem. Cytochem.5, 420 (1957).PubMedGoogle Scholar
  7. 7.
    M.S. Dunhill, Thorax17, 320 (1962).Google Scholar
  8. 8.
    F.G. Zweiman, B.L. Holman, A. O'Keefe, and J. Idoine, J. nucl. Med.16, 975 (1975).PubMedGoogle Scholar
  9. 9.
    D.W. Romhilt, A.B. Ashare, R.J. Adolph, N.I. Levenson, W.G. Wee, V.J. Sodd and L.S. August, J. nucl. Med.17, 247 (1976).PubMedGoogle Scholar
  10. 10.
    M.L. Marcus, R.J. Tomanek, J.C. Ehrhardt, R.E. Kerber, D.D. Brown and F.M. Abboud, Circulation54, 647 (1976).PubMedGoogle Scholar
  11. 11.
    A.J. Roberts, P.R. Cipriano, D.R. Alonso, J.G. Jacobstein, J.R. Combes and W.A. Gay, Circulation57, 35 (1978).PubMedGoogle Scholar
  12. 12.
    Ch.R. Roe and C.F. Starmer, Circulation55, 438 (1977).PubMedGoogle Scholar
  13. 13.
    J.M. Kjekshus and B.E. Sobel, Circulation Res.27, 403 (1970).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1978

Authors and Affiliations

  • H. Braselmann
    • 1
  • Ulrike Osswald
    • 1
  • K. Wenzelides
    • 1
  • E. Seidler
    • 1
  1. 1.Institute of PathologyHumboldt-University BerlinBerlin(German Democratic Republic)

Personalised recommendations