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Radioimmunoassay of free aldosterone and of its 18-oxo-glucuronide in human urine

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Zusammenfassung

Von Kaninchen, die mit einemd-Aldosteron-21-hemisuccinat-Rinderserumalbumin-Komplex immunisiert waren, konnten Aldosteron-Antikörper von ausreichendem Titer und von guter Spezifizität gewonnen werden. Mit Hilfe dieser Antikörper war es möglich, freies Aldosteron und den 18-oxo-Glucuronid-Metaboliten im Urin von gesunden Versuchspersonen und bei Patienten mit veränderter Produktion von Aldosteron zu bestimmen.

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References

  1. D. Mayes, S. Furuyama, D. C. Kem andC. A. Nugent, J. clin. Endocrin.30, 682 (1970).

    Google Scholar 

  2. F. Bayard, I. Z. Beitins, A. Kowarski andC. J. Migeon, J. clin. Endocrin.31, 1 (1970).

    Google Scholar 

  3. F. Bayard, I. Z. Beitins, A. Kowarski andC. J. Migeon, J. clin. Endocrin.31, 507 (1970).

    Google Scholar 

  4. B. Erlanger, F. Borek, S. M. Beiser andS. J. Lieberman, Biol. Chem.228, 713 (1957).

    Google Scholar 

  5. G. E. Abraham, J. clin. Endocrin.29, 866 (1969).

    Google Scholar 

  6. W. Kelly, inImmunologic Methods in Steroid Determination (Eds.F. G. Peron, B. V. Caldwell Meredith, N. Y. 1970), p. 54.

  7. P. Vecsei andH. Kessler, Experientia26, 1015 (1970).

    PubMed  Google Scholar 

  8. Human Serum Globulin:Forschungs-Gamma-Globulin (Deutsche Kabi GmbH, München).

  9. 1 vol. activated coal solution (5 g Norit A, Serva, Heidelberg, in 80 ml γ-globulin buffer solution) +3 vol. Dextran solution (100 mg Dextran T 70), Pharmacia, Uppsala, dissolved in 80 ml γ-globulin-buffer solution. Stirring for 10 min prior to the use.

  10. J. H. Laragh, J. E. Sealey andS. C. Sommer, Circulation Res.18–19, 158 (1966).

    Google Scholar 

  11. M. I. New, B. Miller andR. E. Peterson, J. clin. Invest.45, 412 (1966).

    PubMed  Google Scholar 

  12. A. Aakvaag, Clin. chim. Acta34, 197 (1971).

    Article  PubMed  Google Scholar 

Download references

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Author notes

  1. B. Penke

    Present address: Department of Organic Chemistry of the University Szeged, (Hungary)

Authors and Affiliations

  1. Department of Pharmacology, University of Heidelberg, Hauptstrasse 47-51, D-69, Heidelberg, (Germany)

    P. Vecsei, B. Penke & A. Joumaah

Authors
  1. P. Vecsei
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  2. B. Penke
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  3. A. Joumaah
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Vecsei, P., Penke, B. & Joumaah, A. Radioimmunoassay of free aldosterone and of its 18-oxo-glucuronide in human urine. Experientia 28, 622–624 (1972). https://doi.org/10.1007/BF01931912

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  • DOI: https://doi.org/10.1007/BF01931912

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