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Structural coupling between pancreatic islet cells

Experientia volume 29, pages 1015–1018 (1973)Cite this article

Résumé

Ce travail décrit la présence de spécialisations des membranes plasmatiques entre les cellules endocrines des îlots de Langerhans chez le rat. Ces spécialisations sont révélées par le cryodécapage («freeze-etching») et apparaissent sous la forme de nexus («gap-junctions») ou de jonctions serrées («tight-junctions»). Elles représentent probablement la base structurale d'un couplage ionique et métabolique entre les cellules endocrines.

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Author information

Affiliations

  1. Institutes of Histology and Clinical Biochemistry, University of Geneva, CH-1211, Genève 4, (Switzerland)

    L. Orci, R. H. Unger & A. E. Renold

Authors
  1. L. Orci
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  2. R. H. Unger
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  3. A. E. Renold
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Additional information

We thank M. Sidler-Ansermet and M. Bernard for technical assistance. This work was supported in part by grants from Fonds National Suisse de la Recherche Scientifique and by a grant-in-aid from Hoechst-Pharmaceuticals, Frankfurt-Hoechst, Germany. Preliminary findings (L. Orci, A. E. Lambert, Y. Kanazawa, W. Stauffacher, Ch.Rouiller andA. E. Renold, Diabetes20, 326, 1971) and the present work (L. Orci, R. H. Unger andA. E. Renold, Abstr. 7th ann. meetind Europ. Soc. Clin. Invest., Rotterdam, 1973, p. 157) have been reported in an abstract form.

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Orci, L., Unger, R.H. & Renold, A.E. Structural coupling between pancreatic islet cells. Experientia 29, 1015–1018 (1973). https://doi.org/10.1007/BF01930436

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  • DOI: https://doi.org/10.1007/BF01930436

Keywords

  • Islet Cell
  • Pancreatic Islet
  • Pancreatic Islet Cell
  • Structural Coupling