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The effect of pentagastrin on the A1-cells of the pancreatic islets in guinea-pigs

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Zusammenfassung

Meerschweinchen wurden für 5 Tage mit Pentagastrin injiziert und die Kerngrössen in den Pankreas-Inseln mit Karyometrie bestimmt. Die Kerne der A1-Zellen nahmen in den behandelten Tieren am Anfang ab und schienen kleiner als in den Kontrollen. In den A2-und B-Zellen wurden keine Veränderungen nach Pentagastrin notiert. Die Resultate stützen die Auffassung, dass Gastrin in den A1-Zellen produziert wird.

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Authors and Affiliations

  1. Histological Department, University of Uppsala, V. Ägatan 26 A, S-752 20, Uppsala, Sweden

    B. Petersson

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  1. B. Petersson
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Additional information

The work was supported by grants from the Swedish Medical Research Council No. B70-2297-03. The pentagastrin (Peptavlon) was kindly supplied by Imperial Chemical Industries (ICI).

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Petersson, B. The effect of pentagastrin on the A1-cells of the pancreatic islets in guinea-pigs. Experientia 28, 345–346 (1972). https://doi.org/10.1007/BF01928730

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