Summary
After i.p. application of 1, 0,5 and 0,1 mg p,p' DDT, labelled with3H or14C, to pregnant mice in different stages of pregnancy, the same level of radioactivity was found in the fetal and maternal blood. Starvation for 2 days caused a significant increase of residues, especially in the liver. Residue levels of DDT and its metabolities DDE, DDD, DCB and (DDOH+DDA) are found in fetal and maternal blood, brain liver and fat.
Similar content being viewed by others
Letiratur
J. Bäckström, E. Hanson andS. Ullberg, Toxikol. appl. Pharmakol.7, 90 (1965).
J. K. Finnegan, H. B. Haag andP. S. Larson, Proc. Soc. exp. Biol. Med.72, 357 (1949).
D. L. Harrison andJ. C. M. Mol, Proc. 21. New Zealand Weed Pest Control. Conf. 1968, p. 233.
D. E. Hathway, J. A. Moss, J. A. Rose andD. J. M. Williams, Europ. J. Pharmac.1, 167 (1967).
A. Curley, M. F. Copeland andR. D. Kimbrough, Archs envir. Hlth19, 628 (1969).
R. Engst, R. Knoll andB. Nickel, Pharmazie,24, 673 (1969).
Z. W. Polishuk, M. Wassermann, D. Wassermann, Y. Groner, S. Lazarovici andL. Tomatis, Archs envir. Hlth20, 215 (1970).
M. Beroza, M. N. Inscoe andM. C. Bowman, Residue Rev.30, 1 (1969).
H. Seidler, M. Härtig, M. Kujawa andR. Engst, Nahrung14, 39 (1970).
W. Hayes Jr., W. E. Dale andC. I. Pirkle, Archs envir. Hlth22, 119 (1971).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Schmidt, R., Dedek, W. Transport, verteilung und Metabolismus von3H-und14C-markiertem DDT in graviden mäusen unter hungerbelastung. Experientia 28, 56–57 (1972). https://doi.org/10.1007/BF01928263
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01928263