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Effect of adrenaline on the in vitro enzyme secretion in the guinea-pig pancreas

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Riassunto

In un sistema di fette di pancreas di cavia incubate in vitro l'adrenalina non modifica l'attività secretoria delle cellule acinari né in condizioni basali né in risposta a farmaci segretagoghi (ceruleina e carbamoilcolina). Sembra quindi probabile che l'inibizione della secrezione pancreatica esocrina prodotta in vivo dalla iniezione di adrenalina sia dovuta ad un meccanismo indiretto, quale la vasocostrizione pancreatica e(o) l'inibizione della secrezione di acqua ed elettroliti a livello delle cellule acino-duttulari.

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Authors and Affiliations

  1. Department of Pharmacology, University of Milan, Via Vanvitelli 32, I-20129, Milano, Italy

    J. Meldolesi & G. Macchi

  2. CNR Center of Cytopharmacology, Milan, Italy

    J. Meldolesi & G. Macchi

Authors
  1. J. Meldolesi
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  2. G. Macchi
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Meldolesi, J., Macchi, G. Effect of adrenaline on the in vitro enzyme secretion in the guinea-pig pancreas. Experientia 28, 50–51 (1972). https://doi.org/10.1007/BF01928259

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