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Choline acetyltransferase of human placenta during the first trimester of pregnancy

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Zusammenfassung

Cholinacetyltransferase (ChAc) wurde mit radiometrischer Methode im Homogenat unreifer menschlicher Plazenta bestimmt. Das Enzym war bereits nach 6–7 Wochen Gravidität eindeutig messbar und hatte höhere spezifische Aktivität als dasjenige der reifen Plazenta. Die Ergebnisse lassen vermuten, dass ChAc schon mit Beginn der Plazentation auftritt und unterstützen früher geäusserte Vermutungen, dass ACh in der menschlichen Plazenta bisher noch nicht genauer definierte Aufgaben in der Regulation von Membranpermeabilität und aktivem Transport haben könnte.

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Authors and Affiliations

  1. Department of Pharmacology, B 403 Life Sciences, Michigan State University, 48824, East Lansing, Michigan, USA

    F. Welsch

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  1. F. Welsch
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Additional information

Supported by USPHS grant No. HD 07091-02. The technical assistance of Mrs.Cynthia Knight is gratefully acknowledged.

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Welsch, F. Choline acetyltransferase of human placenta during the first trimester of pregnancy. Experientia 30, 162–163 (1974). https://doi.org/10.1007/BF01927708

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