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Immunosuppressive effect of a mouse placenta fraction on H-2 incompatible split heart allografts

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  • Haematologica, Immunologica
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Summary

A soluble placenta fraction from mice (A.CA) mated with H-2 histoincompatible males (A/Sn) significantly prolonged the survival of heterotopic A/Sn heart transplants in A.CA recipients. No prolongation of A/Sn heart graft survival was obtained with the corresponding A.CA placenta fraction after A.CA × A.CA mating.

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References

  1. J. B. Solomon,Foetal and Neonatal Immunology Frontiers of Biology (Eds.A. Neuberger andE. L. Tatum; North-Holland Publ. Co., Amsterdam 1971), vol. 20.

    Google Scholar 

  2. A. E. Beer andR. E. Billingham, Scient. Am.230, 36 (1974).

    Google Scholar 

  3. R. H. Andresen andC. W. Monroe, Am. J. Obstet. Gynec.84, 1096 (1962).

    PubMed  Google Scholar 

  4. R. H. Buckley, R. I. Schiff andD. B. Amos, J. Immun.108, 34 (1972).

    PubMed  Google Scholar 

  5. R. W. Heslop, P. L. Krohn andE. M. Sparrow, J. Endocr.10, 325 (1954).

    PubMed  Google Scholar 

  6. S. Kasakura, J. Immun.107, 1296 (1971).

    PubMed  Google Scholar 

  7. R. E. Billingham, Am. J. Obstet. Gynec.111, 469 (1971).

    PubMed  Google Scholar 

  8. G. A. Currie, W. Van Doorninck andK. D. Bagshawe, Nature, Lond.219, 192 (1968).

    Google Scholar 

  9. B. J. Martin, S. S. Spicer andN. M. Smythe, Anat. Rec.178, 769 (1974).

    PubMed  Google Scholar 

  10. R. M. Fauve, B. Hevin, H. Jacob, J. A. Gaillard andF. Jacob, Proc. natn. Acad. Sci., USA71, 4052 (1974).

    Google Scholar 

  11. S. F. Contractor andH. Davies, Nature New Biol.243, 284 (1973).

    PubMed  Google Scholar 

  12. J. S. Munroe, J. reticuloend. Soc.9, 361 (1971).

    Google Scholar 

  13. R. Rembiesa, W. Ptak andM. Bubak, Experientia30, 82 (1974).

    Google Scholar 

  14. J. S. Thompson, M. K. Crawford, R. W. Reilly andC. D. Severson, J. Immun.98, 331 (1967).

    PubMed  Google Scholar 

  15. A. H. Glasgow, S. R. Cooperband, K. Schmid, J. T. Parker, J. C. Occhino andJ. A. Mannick, Transpl. Proc.3, 835 (1971).

    Google Scholar 

  16. S.-E. Svehag andW. Schilling, Transplantation,15, 345 (1973).

    Google Scholar 

  17. S. S. Ogra, R. A. Murgita andT. B. Tomasi, Jr., Immun. Commun.3, 497 (1974).

    Google Scholar 

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The work was supported by the Danish Medical Research Council (Project No. 512-3088).

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Svehag, S.E., Schilling, W. Immunosuppressive effect of a mouse placenta fraction on H-2 incompatible split heart allografts. Experientia 32, 1201–1202 (1976). https://doi.org/10.1007/BF01927626

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  • DOI: https://doi.org/10.1007/BF01927626

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