Experientia

, Volume 32, Issue 9, pp 1184–1186 | Cite as

RNA synthesis in α-amanitin-poisoned rats: Prevention of recovery by inhibition of protein synthesis

  • M. Derenzini
  • F. Novello
Specialia Pharmacologica

Summary

The treatment with cycloheximide of rats previously poisoned with α-amanitin hinders the recovery of RNA synthesis observed in the liver of rats treated with α-amanitin alone. The recovery of RNA synthesis can be ascribed to the capability of poisoned rats to synthesize new RNA-polymerase II.

Keywords

Protein Synthesis Cycloheximide 

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • M. Derenzini
    • 1
  • F. Novello
    • 1
  1. 1.Istituto di Patologia Generale dell'UniversitàBologna(Italy)

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