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Effect of lithium on brain aconitase activity

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Résumé

Nous avons déterminé l'activité spécifique de l'aconitase cérébrale des souris après une période de 108 jours de traitement avec du lithium (Li2CO3). Une inhibition significative de l'enzyme à été observée. D'autre part, nous n'avons trouvé in vitro aucun effet du Li2CO3 sur l'aconitase cérébrale.

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Authors and Affiliations

  1. Laboratory of Biochemistry, Department of Chemistry and Experimental Therapeutics, Instituto Oswaldo Cruz, P.O. Box 926-ZC-00, Rio de Janeiro, Brasil

    L. A. Abreu & R. R. Abreu

Authors
  1. L. A. Abreu
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  2. R. R. Abreu
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Additional information

R. R. A. was supported by a research grant from the Conselho Nacional de Pesquisas (National Research Council of Brasil).

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Abreu, L.A., Abreu, R.R. Effect of lithium on brain aconitase activity. Experientia 29, 446–447 (1973). https://doi.org/10.1007/BF01926772

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