Skip to main content
SpringerLink
Log in

Granule alteration and vacuole formation, two primary structural features of the histamine release process in mast cells

  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Die Histaminfreisetzung in peritonealen Mastzellen der Ratte, hervorgerufen durch Toluidinblau, wurde in vitro studiert und festgestellt, dass Toluidinblau vor allem auf die Feinstruktur der Mastzellgranula und deren unmittelbare Umgebung einwirkt, wodurch Cytoplasmabläschen entstehen. Diese setzen sich wahrscheinlich mit dem extra-zellulären Raum in Verbindung, woraus geschlossen wird, dass das Auswandern von Granula aus dem Zellbereich keine Vorbedingung für die Histaminfreisetzung darstellt.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. D. E. Smith, Am. J. Physiol.193, 573 (1958).

    Article  CAS  PubMed  Google Scholar 

  2. P. G. Krüger, B. Diamant andL. Scholander, Expl. Cell. Res.63, 101 (1970).

    Article  Google Scholar 

  3. O. Bank andH. G. Bungenberg de Jong, Protoplasma32, 489 (1939).

    Article  CAS  Google Scholar 

  4. J. W. Kelly,Protoplasmatologia (Springer, Wien 1956), vol. 2.

    Google Scholar 

  5. P. A. Shore, A. Burkholter andV. H. Cohn Jr., J. Pharmac. exp. Ther.127, 182 (1959).

    CAS  Google Scholar 

  6. G. D. Bloom, B. Larsson andD. E. Smith, Acta path. microbiol. scand.40, 308 (1957).

    Google Scholar 

  7. G. D. Bloom andÖ. Haegermark, Expl Cell Res.40, 637 (1965).

    Article  CAS  Google Scholar 

  8. G. D. Bloom andÖ. Haegermark, Acta physiol. scand.71, 257 (1967).

    Article  CAS  PubMed  Google Scholar 

  9. P. G. Krüger, G. D. Bloom andB. Diamant, to be published.

  10. G. D. Bloom andN. Chakravarty, Acta physiol. scand,78, 410 (1970).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Anatomy, University of Bergen, Årstadvollen, Bergen, Norway

    P. -G. Krüger & G. D. Bloom

  2. Dept. of Histology, University of Umeå, Sweden

    P. -G. Krüger & G. D. Bloom

Authors
  1. P. -G. Krüger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. D. Bloom
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

The authors are indebted to MissMarianne Borg for technical assistance and the Swedish Medical Research Council and the Magnus Bergvall Foundation for grants. We also gratefully acknowledge the use of the Stereoscan S-4 scanning electron microscope which is a gift to the University of Umeå from the Knut and Alice Wallenberg Foundation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Krüger, P.G., Bloom, G.D. Granule alteration and vacuole formation, two primary structural features of the histamine release process in mast cells. Experientia 29, 329–330 (1973). https://doi.org/10.1007/BF01926508

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01926508

Keywords

Search

Navigation