Zusammenfassung
Nachweis, dass neugeborene Ratten (bis zum 8. Tag), die intracerebral mit 6-OH-Dopamin behandelt wurden, am 35. Lebenstag eine Überempfindlichkeit gegenüber der Adenylzyklase-stimulierenden Wirkung von Noradrenalin aufweisen.
Literatur
G. C. Palmer, F. Sulser andG. A. Robison, Neuropharmacology12, 327 (1973).
G. C. Palmer, Neuropharmacology11, 145 (1972).
A. Kalisker, C. O. Rutledge andJ. P. Perkins, Molec. Pharmac.9, 619 (1973).
G. R. Siggins, E. F. Battenberg, B. J. Hoffer, F. E. Bloom andA. L. Steiner, Science179, 585 (1973).
F. E. Bloom, S. Algeri, A. Groppetti, A. Revuelta andE. Costa, Science166, 1284 (1969).
U. Ungerstedt, Eur. J. Pharmac.5, 107 (1968).
N. J. Uretsky andL. L. Iversen, J. Neurochem.17, 269 (1970).
G. R. Breese andT. D. Traylor, Br. J. Pharmac.44, 210 (1972).
D. M. Jacobowitz, inFrontiers in Catecholamine Research, III International Catecholamine Symposium, 1973, in press.
K. Nakamura andH. Thoenen, Psychopharmacologia24, 359 (1972).
H. C. Agrawal, S. N. Glisson andW. A. Himwich, Biochim. biophys. Acta130, 511 (1966).
G. K. Aghajanian andF. E. Bloom, Brain Res.6, 716 (1967).
M. J. Schmidt, G. C. Palmer, W.-D. Dettbarn andG. A. Robison, Devel. Psychobiol.3, 53 (1970).
B. Singh andJ. de Champlain, Brain Res.48, 432 (1972).
O. Castren, M. Airaksinen andS. Saarikoski, Experientia29, 576 (1973).
I. Creese andS. D. Iversen, Brain Res.55, 369 (1972).
J. de Champlain andR. Nadeau, Fedn. Proc.30, 877 (1971).
J. F. Giudicelli, Experientia27, 1194 (1971).
G. M. Lew andW. B. Quay, Res. Commun. Chem. Path. Pharmac.2, 807 (1971).
Author information
Authors and Affiliations
Additional information
This investigation was supported by a research grant awarded by the National Institute of Mental Health No. MH 21584.
Rights and permissions
About this article
Cite this article
Palmer, G.C., Scott, H.R. The cyclic AMP response to noradrenalin in young adult rat brain following post-natal injections of 6-hydroxydopamine. Experientia 30, 520–521 (1974). https://doi.org/10.1007/BF01926327
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01926327