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Dérivés trifluorométhylés des [1]benzothiopyrano[4,3-b]indoles et des 6H-[1]benzothiopyrano-[4,3-b]quinoléines

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Summary

Some fluoro derivatives of [1]benzothiopyrano[4,3-b]indoles and 6H[1]benzothiopyrano[4,3-b] quinolines have shown carciuogenic activities in regard to the fluorine position; we thought it interesting to prepare some trifluoromethyl analogs of there compounds to study the biological activities and to compare with other compounds of the same family. In the present work, we report the synthesis of 7-trifluoromethyl and 8-trifluoromethyl [1]thiochroman-4-one and some [1]benzothiopyrano[4,3-b]indoles and quinolines substitued in 3 or 4 position which have been obtained from these two ketones.

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Authors and Affiliations

  1. Institut de Chimie des Substances Naturelles du CNRS, 91190, Gif sur Yvette, France

    P. Jacquignon, A. Fravolini, A. Feron & A. Croisy

  2. Instituto di Chimica Farmaceutica e Tossicologica, Università degli Studi, Perugia, Italie

    P. Jacquignon, A. Fravolini, A. Feron & A. Croisy

  3. Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Domaine Universitaire du Sart-Tillman, 1B-4000, Liège, Belgique

    P. Jacquignon, A. Fravolini, A. Feron & A. Croisy

Authors
  1. P. Jacquignon
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  2. A. Fravolini
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  3. A. Feron
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  4. A. Croisy
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Jacquignon, P., Fravolini, A., Feron, A. et al. Dérivés trifluorométhylés des [1]benzothiopyrano[4,3-b]indoles et des 6H-[1]benzothiopyrano-[4,3-b]quinoléines. Experientia 30, 452–455 (1974). https://doi.org/10.1007/BF01926287

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  • DOI: https://doi.org/10.1007/BF01926287

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