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Lichtinduzierte Reaktionen des 4-n-Butyl-1,2-diphenylpyrazolidin-3,5-dion (Phenylbutazon) mit nucleophilen Agentien

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Summary

The light-induced fragmentation of 4-n-butyl-1,2-diphenyl-pyrazolidindione-3,5 is described. In the presence of protonic, nucleophilic agents, the C−N bond of the intermediate aziridinone is split and3a-c resp.4, 6 and7 are formed.

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Literatur

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Authors and Affiliations

  1. Institut für Pharmazeutische Chemie der Westfälischen Wilhelms-Universität Münster, D-44, Münster/Westf, Bundesrepublik Deutschland

    J. Reisch, K. G. Weidmann & J. Triebe

  2. Bundeswehrapotheke Detmold, Bundesrepublik Deutschland

    J. Reisch, K. G. Weidmann & J. Triebe

Authors
  1. J. Reisch
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  2. K. G. Weidmann
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  3. J. Triebe
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Additional information

30. Mitt.: Photo- und Strahlenchemische Studien. 29. Mitt.:J. Reisch undW. Köbberling, Pharmazie, im Druck.

Aus der in Vorbereitung befindlichen DissertationJ. Triebe.

Der Deutschen Forschungsgemeinschaft danken wir für Sachbeihilfen.

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Reisch, J., Weidmann, K.G. & Triebe, J. Lichtinduzierte Reaktionen des 4-n-Butyl-1,2-diphenylpyrazolidin-3,5-dion (Phenylbutazon) mit nucleophilen Agentien. Experientia 30, 451–452 (1974). https://doi.org/10.1007/BF01926286

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  • DOI: https://doi.org/10.1007/BF01926286

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