Alterations in fetal rabbit prothrombin time at different stages of gestation and during asphyxia

  • A. A. Orekhova


Experiments were conducted which demonstrated that prothrombin time diminishes gradually during gestation of the fetuses. The suggestion is made that this may be associated with the appearance of the prothrombin formation function of the liver. This function is not fully developed at birth but centinues maturing. This and not vitamin K deficiency is suggested as the reason for the comparatively prolonged prothrombin time seen during the first few days of independent life. Prothrombin time is greatly increased by asphyxia.


Fibrinogen Prothrombin Prothrombin Time Tmcs Independent Life 
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Copyright information

© Consultants Bureau, Inc. 1957

Authors and Affiliations

  • A. A. Orekhova
    • 1
  1. 1.Biochemical Laboratory and Section for Newborn Institute of Obstetrics and GynecologyAMN SSSRLeningrad

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