, Volume 32, Issue 12, pp 1538–1540 | Cite as

The influence of early nutrition and environmental rearing on brain growth and behaviour

  • V. R. Sara
  • T. L. King
  • L. Lazarus


Preweaning malnutrition permanently reduced brain size and cellular content but in spite of changes in the adrenocortical stress response no learning deficit was observed. Differential rearing environments did not influence the effects of malnutrition.


Stress Response Brain Size Cellular Content Brain Growth Learning Deficit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 3.
    R. H. Barnes, Fedn. Proc.30, 1429 (1971).Google Scholar
  2. 4.
    D. A. Blizard andC. T. Randt, Nature, Lond.251, 705 (1974).Google Scholar
  3. 5.
    M. C. Latham, Physiol. Rev.54, 541 (1974).PubMedGoogle Scholar
  4. 6.
    M. Winick, Clin. Obstet. Gynaec.13, 526 (1970).Google Scholar
  5. 7.
    S. Zamenhof, E. van Marthens andL. Grauel, J. Nutr.101, 1265 (1971).PubMedGoogle Scholar
  6. 8.
    D. Krech, M. R. Rosenzweig andE. L. Bennett, J. comp. Physiol. Psych.55, 801 (1952). —M. R. Rosenzweig, Am. Psychol.21, 321 (1966).Google Scholar
  7. 9.
    S. Fraňková,Malnutrition, Learning and Behaviour (Eds.N. S. Scrimshaw andJ. E. Gordon; MIT, Cambridge 1968), p. 312.Google Scholar
  8. 10.
    D. A. Levitsky andR. H. Barnes, Science176, 68 (1972).PubMedGoogle Scholar
  9. 11.
    M. G. McCall, G. E. Newman, J. R. P. O'Brien, J. S. Valberg andL. J. Witts, J. Nutr.16, 297 (1962).Google Scholar
  10. 12.
    V. R. Sara andL. Lazarus, Nature, Lond.250, 257 (1974).Google Scholar
  11. 13.
    K. W. Spence, K. P. Goodrich andL. E. Ross J. exp. Psychol.58, 8 (1959).PubMedGoogle Scholar
  12. 14.
    B. E. P. Murphy, J. clin. Endocr. Metab.27, 973 (1967).PubMedGoogle Scholar
  13. 15.
    H. N. Munro andA. Fleck, Meth. biochem. Analysis14, 113 (1966).Google Scholar
  14. 16.
    H. Scheffé,The Analysis of Variance (Wiley, New York 1959).Google Scholar
  15. 17.
    J. Dobbing,Scientific Foundations of Paediatrics (Eds.J. A. Davis andJ. Dobbing, (Heineman, London, 1974), p. 565.Google Scholar
  16. 18.
    S. Fraňková andR. H. Barnes, J. Nutr.96, 485 (1968).PubMedGoogle Scholar
  17. 19.
    S. L. Giurintano, Physiol. Behav.12, 55 (1974).CrossRefPubMedGoogle Scholar
  18. 20.
    P. D. Leathwood, M. S. Bush, C. D. Berent andJ. Mauron, Life Sci.14, 157 (1974).CrossRefPubMedGoogle Scholar
  19. 21.
    B. P. F. Adlard andJ. L. Smart, J. Endocr.54, 99 (1972).PubMedGoogle Scholar
  20. 22.
    D. A. Levitsky andR. H. Barnes, Nature225, 468 (1970).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • V. R. Sara
    • 1
  • T. L. King
    • 1
  • L. Lazarus
    • 1
  1. 1.Garvan Institute of Medical ResearchSt. Vincent's HospitalSydneyAustralia

Personalised recommendations