Skip to main content
Log in

Changes in 80S ribosomes fromDrosophila melanogaster with age

  • Specialia
  • Chimica, Biochimica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

A 23% reduction in the amount of 80S ribosomes extracted from young and old maleDrosophila melanogaster on a per g wet weight basis was demonstrated. Furthermore, a significant alteration in the structural integrity of the ribosomal RNA-protein complex from older flies as demonstrated by the dissociation of protein from the 80S particle in the presence of varying concentrations of KCl was observed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. M. Rockstein andJ. Miquel, inThe Physiology of Insecta, 2nd ed., vol. 1 (Ed.M. Rockstein; Academic Press, New York 1973), p. 371.

    Chapter  Google Scholar 

  2. P. S. Chen, inMolecular Genetic Mechanisms in Development and Aging (EdsM. Rockstein andG. T. Baker; Academic Press, New York 1972), p. 199.

    Google Scholar 

  3. G. T. Baker, Gerontologia22, 334 (1976).

    Article  CAS  Google Scholar 

  4. J. M. Wattiaux, M. Libion-Mannaert andJ. Delcour, Gerontologia17, 289 (1971).

    Article  CAS  PubMed  Google Scholar 

  5. A. G. Lambertsson, Molec. gen. genet.128, 241 (1974).

    Article  CAS  PubMed  Google Scholar 

  6. G. T. Baker, Gerontologia21, 203 (1975).

    Article  CAS  PubMed  Google Scholar 

  7. J. Delaunay, F. Crensot andG. Schapira, Biochimie56, 189 (1974).

    Article  CAS  PubMed  Google Scholar 

  8. G. T. Baker, Exp. geront.10, 231 (1975).

    Article  CAS  Google Scholar 

  9. T. Schmidt andG. T. Baker, (in preparation).

  10. R. Johnson andB. L. Strehler, Nature240, 412 (1972).

    Article  CAS  PubMed  Google Scholar 

  11. G. T. Baker andW. Hennig, (in preparation).

  12. P. A. Baumann andP. S. Chen, Rev. suisse zool.75, 1051 (1968).

    Google Scholar 

  13. L. Levenbook andI. Krishna, J. insect. physiol.17, 9 (1971).

    Article  CAS  PubMed  Google Scholar 

  14. M. Rockstein andG. T. Baker, Mech. age dev.3, 271 (1974).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Acknowledgments. We thank Drs Chen and Kubli for their critical reading of the manuscript. This work was supported by grants from the Georges-und-Antoine-Cleraz-Schenkung and Karl-Hescheler-Stiftung.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Baker, G.T., Schmidt, T. Changes in 80S ribosomes fromDrosophila melanogaster with age. Experientia 32, 1505–1506 (1976). https://doi.org/10.1007/BF01924419

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01924419

Keywords

Navigation