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Nuclear RNA and protein metabolism in lethal heterospecific amoeba

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Zusammenfassung

In heterospezifischen Zellen, welche durch Transplantation des Zellkerns vonAmoeba amazonas in kernlose Zellen vonAmoeba proteus erhalten wurden (begrenzt lebensfähig und nicht mehr teilungsfähig), nimmt die intranukleäre RNS-Synthese im Laufe der Versuchsperiode kontinuierlich ab, während sie in Kerntransplantationsversuchen zwischen Zellen derselben Art konstant bleibt. Diese Unfähigkeit der Hybridenzellen, ihre nukleäre RNS-Synthese aufrechtzuerhaltten, ist mit keinem nachweisbaren Effekt auf den Proteinstoffwechsel des Zellkerns verbunden.

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I am indebted to Prof.Lester Goldstein for his encouragement and criticism. This work was supported by a USPHS grant to Prof.L. Goldstein.

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Chatterjee, S. Nuclear RNA and protein metabolism in lethal heterospecific amoeba. Experientia 30, 1149–1150 (1974). https://doi.org/10.1007/BF01923658

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