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Increased synchrony of DNA synthesis in regenerating rat liver after continous infusion of hydroxyurea

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Zusammenfassung

Intravenöse Dauerinfusion von Hydroxyharnstoff bis zu 40 h nach partieller Hepatektomie inhibiert den Beginn der DNA-Synthese in der Rattenleber. Nach Aufhebung des Blocks treten Hepatozyten subtotal synchronisiert in die DNA-Synthese ein. Ein ähnlich hoher Synchronie-Grad wurde bisher in vivo nicht erreicht.

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Authors and Affiliations

  1. Institute of Pathology, University of Munich, Thalkirchner Strasse 36, D-8, München 2, Germany

    H. M. Rabes, G. Iseler, H. V. Tuczek & R. Kerler

Authors
  1. H. M. Rabes
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  2. G. Iseler
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  3. H. V. Tuczek
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  4. R. Kerler
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Supported by grants from Deutsche Forschungsgemeinschaft.

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Rabes, H.M., Iseler, G., Tuczek, H.V. et al. Increased synchrony of DNA synthesis in regenerating rat liver after continous infusion of hydroxyurea. Experientia 30, 1116–1117 (1974). https://doi.org/10.1007/BF01923640

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  • DOI: https://doi.org/10.1007/BF01923640

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