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Shape change of human blood platelets: Reliable and fast detection by quasi-elastic light scattering

Experientia volume 48, pages 71–79 (1992)Cite this article

Abstract

Quasi-elastic light scattering has been used for the first time to obtain reliable information about the morphology of platelets under physiological conditions within a short time. By measuring two independent parameters (electrophoretic mobility and diffusion coefficient) it is possible to distinguish between different stages of shape change on the one hand, and between shape change and binding of particles to the platelet surface without shape change on the other hand.

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Author information

Affiliations

  1. Institut für Physikalische Chemie, Universität Graz, A-8010, Graz, Austria

    E. Spurej & O. Glatter

  2. Institut für Histologie, Universität Graz, A-8010, Graz, Austria

    G. Pfeiler

Authors
  1. E. Spurej
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  2. O. Glatter
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  3. G. Pfeiler
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Spurej, E., Glatter, O. & Pfeiler, G. Shape change of human blood platelets: Reliable and fast detection by quasi-elastic light scattering. Experientia 48, 71–79 (1992). https://doi.org/10.1007/BF01923612

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  • DOI: https://doi.org/10.1007/BF01923612

Key words

  • Light scattering
  • electrophoresis
  • platelets
  • shape change
  • hyperlipaemia